The TRANSDIA project

TRANSDIA is a collaboration to establish an islet isolation and transplant program in Mexico to help children and young adults with diabetes type 1. The partners also aim to undertake an innovative pre-clinical study that has potential to overcome current challenges and improve transplantation success. To find out more click here.

The TRANSDIA partners

TRANSDIA involves a collaboration between the Center for Molecular and Cell-based Therapeutics and the NIH Organ Donor Network in Mexico City, and Oxford Expression Technologies Ltd, Oxford Brookes University and the Oxford Islet Transplant Consortium in the UK.

TRANSDIA funding

The TRANSDIA project is funded through the Newton Fund – UK-Mexico Collaborative Industrial R&D Program. In the UK, funding has been provided by Innovate UK, the UK government’s innovation agency. In Mexico, funding has been provided by CONACYT.


OET at IPITA 2017 – 20th/23rd June







This week staff from

This week staff from OET will be attending the 16th International Pancreatic and Islet Transplantation Association Congress. This is the first time the congress will be held in the UK, and fortunately for us it will be right here in Oxford.


IPITA is dedicated to the advancement of insulin producing tissue transplantation for the treatment of human diabetes. The programme will cover aspects of both research and clinical practices.


As part of our ongoing work for the TRANSDIA project, which aims to increase the success of islet transplantation by pre-transplant gene therapy, we hope that the visit will be highly beneficial. It will provide our scientists the opportunity to share knowledge and experience with experts from around the world, gaining valuable insight which can be applied to our own research.


If you would like more information on the event please click on the link http://www.ipita2017.org/

Opening the Centre for molecular and Cell-Based Therapeutics (CMCBT) Lab

cmcbtMembers of the TRANSDIA team visited the Centre for Molecular and Cell-based Therapeutics (CMCBT) lab in Mexico City, where Professor Linda King in her role as Pro Vice-Chancellor Research & Global Partnerships at Oxford Brookes University, cut a ribbon to officially open the new suite of laboratories in Mexico City.


team-transdiaMembers of the TRANSDIA consortium took part in an inaugural symposium to celebrate the launch of the international research collaboration in Mexico City (October 25th 2016).  From the left, participants were Fernanda Murgui-Meca (CMCBT), Dr Adam Chambers (OET), Professor Robert Possee (OET), Professor Linda King (Oxford Brookes University), Professor Paul Johnson University of Oxford), Dr Stephen Hughes (University of Oxford), Mine Aksular (OET), Dr Juan Jose Plata-Munoz (CMCBT). The symposium included talks that ranged from the public health issues of Diabetes type I in Mexico, to the Oxford islet transplant programme and potential gene therapy using virus vectors, as well as an official TRANSDIA opening remarks from the UK and Mexico.

11/10/2016-Inaugural TRANSDIA Symposium

The TRANSDIA international consortium starts with a symposium at the El Centro Medico Nacional “20 de Noviembre” on the 25th and 26th of October 2016 in Mexico City. Click here to see the program of events for the 25th and 26th. We are delighted that the ceremony to celebrate this UK-Mexico collaboration will be hosted by Marie-Beatrice and Duncan Taylor CBE, British Ambassador in Mexico.

March 2017-OET at ISBiotech

Professor Linda King gave a presentation at the ISBiotech Spring Meeting in the Baculovirus Expression track, entitled ‘BacMam expression vectors: applications in gene therapy”.  In her presentation Professor King explained the work of the TRANSDIA project in using innovative BacMam vectors to deliver genes into pancreatic islet tissues. Find the program here.

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